منابع مشابه
Aleukemic leukemia cutis.
A 46-year-old man presented with nodular skin lesions, a biopsy specimen of which demonstrated a poorly differentiated malignancy. Touch preparations with histochemical staining and electron microscopy confirmed leukemia cutis. Results from a bone marrow aspirate disclosed focal areas of increased myeloblasts, and cytogenetic analysis revealed an abnormal karyotype as follows 46,XY, t(1;2) (q44...
متن کاملNeonatal leukemia cutis presenting with dysmorphic features and cutis laxa
Congenital leukemia is a rare disease with particular biological and clinical characteristics, which differs from those of older children. Its prognosis is generally poor. Its clinical manifestation may vary (hyperleukocytosis, thrombocytopenia, organomegaly) and some patients can develop cutaneous infiltration by leukemic cells (leukemia cutis). We describe a dysmorphic patient with thrombocyt...
متن کاملCD163 expression in leukemia cutis.
BACKGROUND Proper diagnosis of myeloid leukemia cutis (LC) is of great clinical importance but can be difficult because no single immunohistochemical marker is adequately sensitive or specific for definitive diagnosis. Thus, a broader panel of markers is often desirable. CD163 is highly specific for normal and neoplastic cells of the monocyte/histiocyte lineage. In this study, we examined the v...
متن کاملA case of leukemia cutis.
We report a case of leukemia cutis with atypical skin manifestations, presented with generalized various sized dark brownish to erythematous patches with plaques on the whole body of a 42-year-old man. Skin lesions developed 6 months ago and had no signs of itching or tenderness. He complained of sustaining fevers with abdominal discomfort. Laboratory findings showed elevation of leukocyte coun...
متن کاملMyelodysplastic Syndrome Complicated with Leukemia Cutis
We herein presented a 50-year-old female of myelodysplastic syndrome sub-typing refractory anemia with excess blasts. She had received conservative and immunosuppressive therapies, but not controlled well. One year later, multiple asymptomatic, erythematous papules, plaques and nodules developed over trunk and four limbs. The histopathological and immunohistochemical studies showed atypical mon...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2015
ISSN: 0022-202X
DOI: 10.1038/jid.2015.146